Nano & Micro Technology
A number of faculty members in the Chemical and Bimolecular Engineering are seeking to understand and exploit the physical, chemical and biological properties of nano and micro structures.
The research themes include:
- The fabrication of nanostructures (fabricated using chemical vapor deposition, electrodeposition and e-beam lithography) and microstructures (fabricated using photolithography, etch, soft-lithography)
- The directed and self assembly of nano and microscale hierarchical and three dimensional, functional microsystems.
- The manipulation of nanoscale objects in fluidic flows and at fluidic interfaces;
- The fabrication and measurement of molecular based devices including organic semiconductors, functional monolayers.
- Development of multi-functional polymeric nanosystems for tissue- and cell- targeted delivery of therapeutics. Applications include cancer, inflammatory diseases, and gene therapy.
Representative Images
Participating Faculty
Michael Bevan
Marc Donohue
German Drazer
Joelle Frechette
Sharon Gerecht
David Gracias
Jeffrey Gray
Justin Hanes
Joseph Katz
Kathleen Stebe
Denis Wirtz
Representative Publications
- “Diameter-Dependent Modulation of the Polarization Anisotropy in Raman Spectra of Individual Nanowires”, J. Frechette and C. Carraro, Physical Review B, 74, 161404 (2006 ).
- "The Effect of Actin Disrupting Agents on Contact Guidance of Human Embryonic Stem Cells", Gerecht S*, Bettinger* CJ, Zhang Z, Borenstein J, Vunjak-Novakovic G, Langer R. Biomaterials. 28:4068-4077 (2007).
- "Fabrication of Complex Architectures Using Electrodeposition into Patterned Self Assembled Monolayers". Noshir S. Pesika, A. Radisic, Kathleen J. Stebe,* and Peter C. Searson* (* corresponding authors) Nanoletters, 6 (5), 1023-1026 (2006).
- "Gene delivery to differentiated neurotypic cells with RGD and HIV Tat peptide functionalized polymeric nanoparticles", J. S. Suk, J. Suh, K. L. Choy, S. K. Lai, J. Fu and J. Hanes, Biomaterials 27: 5143-5150 (2006).
- "Separation of Suspended Particles by Arrays of Obstacles in Microfluidic Devices", Z. Li, G. Drazer, Phys. Rev. Lett. 98, 050602(2007).
- "Single-molecule analysis of cadherin-mediated cell-cell adhesion", P. Panorchan, M. S. Thompson, K. J. Davis, Y. Tseng, K. Konstantopoulos, and D. Wirtz, Journal of Cell Science 119: 66-73 (2006).
- "Spatially Controlled Chemistry Using Remotely Guided Nanoliter Scale Containers", T. Leong, Z. Gu, T. Koh and D. H. Gracias, Journal of the American Chemical Society 128 (35) 11336-11337 (2006).
